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Mitogen-Activated Protein Kinase Kinase 6 (MAP2K6) (N-Term) Peptide

MAP2K6 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN5512415
  • Target See all MAP2K6 products
    MAP2K6 (Mitogen-Activated Protein Kinase Kinase 6 (MAP2K6))
    Protein Region
    N-Term
    Origin
    Human
    Source
    • 2
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Sequence
    MSQSKGKKRN PGLKIPKEAF EQPQTSSTPP RDLDSKACIS IGNQNFEVKA
    Characteristics
    This is a synthetic peptide designed for use in combination with anti- MAP2K6 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    MAP2K6 (Mitogen-Activated Protein Kinase Kinase 6 (MAP2K6))
    Synonyms
    MAPKK6 Peptide, MEK6 Peptide, MKK6 Peptide, PRKMK6 Peptide, SAPKK-3 Peptide, SAPKK3 Peptide, Mkk6 Peptide, Prkmk6 Peptide, MKK3 Peptide, map2k3 Peptide, zMKK3 Peptide, map2k6 Peptide, mitogen-activated protein kinase kinase 6 Peptide, mitogen-activated protein kinase kinase 6 L homeolog Peptide, MAP2K6 Peptide, Map2k6 Peptide, map2k6 Peptide, map2k6.L Peptide
    Background
    This gene encodes a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis.

    Alias Symbols: MEK6, MKK6, MAPKK6, PRKMK6, SAPKK3, SAPKK-3

    Protein Size: 334
    Gene ID
    5608
    NCBI Accession
    NM_002758, NP_002749
    UniProt
    P52564
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