Transforming Growth Factor, beta Receptor III (TGFBR3) (Middle Region) Peptide
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- Target See all TGFBR3 products
- TGFBR3 (Transforming Growth Factor, beta Receptor III (TGFBR3))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- PFPFPDISRR VWNEEGEDGL PRPKDPVIPS IQLFPGLREP EEVQGSVDIA
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- TGFBR3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- TGFBR3 (Transforming Growth Factor, beta Receptor III (TGFBR3))
- Synonyms
- TGFBR3 Peptide, DKFZp469I0915 Peptide, BGCAN Peptide, betaglycan Peptide, 1110036H20Rik Peptide, AU015626 Peptide, AW215636 Peptide, TBRIII Peptide, transforming growth factor beta receptor 3 Peptide, transforming growth factor, beta receptor III Peptide, TGFBR3 Peptide, tgfbr3 Peptide, Tgfbr3 Peptide
- Background
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This locus encodes the transforming growth factor (TGF)-beta type III receptor. The encoded receptor is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
Alias Symbols: BGCAN, betaglycan
Protein Size: 851 - Gene ID
- 7049
- NCBI Accession
- NM_001195683, NP_001182612
- UniProt
- Q03167
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