Toll-Like Receptor Adaptor Molecule 1 (TICAM1) (C-Term) Peptide
TICAM1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all TICAM1 products
- TICAM1 (Toll-Like Receptor Adaptor Molecule 1 (TICAM1))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- PFPQSPAFPT ASPAPPQSPG LQPLIIHHAQ MVQLGLNNHM WNQRGSQAPE
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-TICAM1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- TICAM1 (Toll-Like Receptor Adaptor Molecule 1 (TICAM1))
- Synonyms
- IIAE6 Peptide, MyD88-3 Peptide, PRVTIRB Peptide, TICAM-1 Peptide, TRIF Peptide, AW046014 Peptide, AW547018 Peptide, trif Peptide, toll like receptor adaptor molecule 1 Peptide, toll-like receptor adaptor molecule 1 Peptide, TICAM1 Peptide, Ticam1 Peptide, ticam1 Peptide
- Background
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This gene encodes an adaptor protein containing a Toll/interleukin-1 receptor (TIR) homology domain, which is an intracellular signaling domain that mediates protein-protein interactions between the Toll-like receptors (TLRs) and signal-transduction components. This protein is involved in native immunity against invading pathogens. It specifically interacts with toll-like receptor 3, but not with other TLRs, and this association mediates dsRNA induction of interferon-beta through activation of nuclear factor kappa-B, during an antiviral immune response.
Alias Symbols: TRIF, IIAE6, MyD88-3, PRVTIRB, TICAM-1
Protein Size: 712 - Gene ID
- 148022
- NCBI Accession
- NM_182919, NP_891549
- UniProt
- Q8IUC6
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