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NEDD8 Activating Enzyme E1 Subunit 1 (NAE1) (Middle Region) Peptide

NAE1 Reactivity: Mouse Host: Synthetic BP, WB
Catalog No. ABIN5512872
$160.46
Plus shipping costs $50.00
100 μg
Shipping to: United States
Delivery in 11 to 17 Business Days

Quick Overview for NEDD8 Activating Enzyme E1 Subunit 1 (NAE1) (Middle Region) Peptide (ABIN5512872)

Target

NAE1 (NEDD8 Activating Enzyme E1 Subunit 1 (NAE1))

Origin

Mouse

Source

  • 1
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    Middle Region

    Sequence

    KNENGAPEDE ENFEEAIKNV NTALNTTQIP SSIEDIFNDD RCINITKQTP

    Characteristics

    This is a synthetic peptide designed for use in combination with NAE1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Storage

    -20 °C

    Storage Comment

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    NAE1 (NEDD8 Activating Enzyme E1 Subunit 1 (NAE1))

    Background

    The protein encoded by this gene binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. In addition, the encoded protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. This protein is required for cell cycle progression through the S/M checkpoint. Three transcript variants encoding different isoforms have been found for this gene.

    Alias Symbols: HPP1, ula-1, APPBP1, A-116A10.1

    Protein Size: 534

    Gene ID

    8883

    NCBI Accession

    NP_001018169
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