NEDD8 Activating Enzyme E1 Subunit 1 (NAE1) (Middle Region) Peptide
Quick Overview for NEDD8 Activating Enzyme E1 Subunit 1 (NAE1) (Middle Region) Peptide (ABIN8106258)
Target
Origin
Source
Application
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Protein Region
- Middle Region
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Purpose
- NAE1 Peptide - middle region
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Sequence
- KNENGAPEDE ENFEEAIKNV NTALNTTQIP SSIEDIFNDD RCINITKQTP
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with NAE1 Antibody (ARP76804_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- NAE1 (NEDD8 Activating Enzyme E1 Subunit 1 (NAE1))
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Background
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Background Information: The protein encoded by this gene binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. In addition, the encoded protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. This protein is required for cell cycle progression through the S/M checkpoint. Three transcript variants encoding different isoforms have been found for this gene.
Alternative Symbols: HPP1, ula-1, APPBP1, A-116A10.1
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Molecular Weight
- 60 kDa
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Gene ID
- 8883
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NCBI Accession
- NP_001018169
Target
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