Granzyme H (Cathepsin G-Like 2, Protein H-CCPX) (GZMH) (C-Term) Peptide
GZMH
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all GZMH products
- GZMH (Granzyme H (Cathepsin G-Like 2, Protein H-CCPX) (GZMH))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- EVLLTVQKDC QCERLFHGNY SRATEICVGD PKKTQTGFKG DSGGPLVCKD
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-GZMH Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- GZMH (Granzyme H (Cathepsin G-Like 2, Protein H-CCPX) (GZMH))
- Synonyms
- GZMH Peptide, CCP-X Peptide, CGL-2 Peptide, CSP-C Peptide, CTLA1 Peptide, CTSGL2 Peptide, granzyme H Peptide, LOC617313 Peptide, GZMH Peptide
- Background
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The protein encoded by this gene is a member of the granzyme family. Members of this family are highly conserved serine proteases that eliminate transformed cells and virus-infected cells. This protein, which has chymotrypsin-like activity, has a preference for bulky aromatic amino acids at the P1 position and for acidic residues at the P3' and P4' positions. This protein is reported to be constitutively expressed in NK cells and may play a role in the cytotoxic arm of the innate immune response by inducing target cell death and by directly cleaving substrates in pathogen-infected cells. Alternative splicing results in multiple transcript variants that encode different protein isoforms.
Alias Symbols: GZMH,CGL2,CTSGL2,
Protein Size: 246 - Gene ID
- 2999
- NCBI Accession
- NP_219491
- UniProt
- P20718
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