Granzyme H (Cathepsin G-Like 2, Protein H-CCPX) (GZMH) (Middle Region) Peptide
GZMH
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all GZMH products
- GZMH (Granzyme H (Cathepsin G-Like 2, Protein H-CCPX) (GZMH))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- RDDFVLTAAH CWGSSINVTL GAHNIKEQEP TQQFIPVKRP IPHPAYNPKN
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-GZMH Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- GZMH (Granzyme H (Cathepsin G-Like 2, Protein H-CCPX) (GZMH))
- Synonyms
- GZMH Peptide, CCP-X Peptide, CGL-2 Peptide, CSP-C Peptide, CTLA1 Peptide, CTSGL2 Peptide, granzyme H Peptide, LOC617313 Peptide, GZMH Peptide
- Background
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This gene encodes a member of the peptidase S1 family of serine proteases. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate a chymotrypsin-like protease. This protein is reported to be constitutively expressed in the NK (natural killer) cells of the immune system and may play a role in the cytotoxic arm of the innate immune response by inducing target cell death and by directly cleaving substrates in pathogen-infected cells. This gene is present in a gene cluster with another member of the granzyme subfamily on chromosome 14.
Alias Symbols: CCP-X, CGL-2, CSP-C, CTLA1, CTSGL2
Protein Size: 160 - Gene ID
- 2999
- NCBI Accession
- NM_001270781, NP_001257710
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