Integrin beta 3 Binding Protein (Beta3-Endonexin) (ITGB3BP) (N-Term) Peptide
ITGB3BP
Reactivity: Human
Host: Synthetic
BP, WB
-
- Target See all ITGB3BP products
- ITGB3BP (Integrin beta 3 Binding Protein (Beta3-Endonexin) (ITGB3BP))
- Protein Region
- N-Term
- Origin
- Human
-
Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- QMSLFASPTS SEEQKHRNGL SNEKRKKLNH PSLTESKEST TKDNDEFMML
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-ITGB3BP Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
-
- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
- Target
- ITGB3BP (Integrin beta 3 Binding Protein (Beta3-Endonexin) (ITGB3BP))
- Synonyms
- CENP-R Peptide, CENPR Peptide, HSU37139 Peptide, NRIF3 Peptide, TAP20 Peptide, 4930471O16Rik Peptide, AU022583 Peptide, integrin subunit beta 3 binding protein Peptide, integrin beta 3 binding protein (beta3-endonexin) Peptide, ITGB3BP Peptide, Itgb3bp Peptide
- Background
-
This gene encodes a transcriptional coregulator that binds to and enhances the activity of members of the nuclear receptor families, thyroid hormone receptors and retinoid X receptors. This protein also acts as a corepressor of NF-kappaB-dependent signaling. This protein induces apoptosis in breast cancer cells through a caspase 2-mediated signaling pathway. This protein is also a component of the centromere-specific histone H3 variant nucleosome associated complex (CENP-NAC) and may be involved in mitotic progression by recruiting the histone H3 variant CENP-A to the centromere. Alternate splicing results in multiple transcript variants.
Alias Symbols: ITGB3BP,CENPR,NRIF3,
Protein Size: 216 - Gene ID
- 23421
- NCBI Accession
- NP_055103
-
You are here:
