Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 6 (PSMC6) (Middle Region) Peptide
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- Target See all PSMC6 products
- PSMC6 (Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 6 (PSMC6))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- VDPLVYNMSH EDPGNVSYSE IGGLSEQIRE LREVIELPLT NPELFQRVGI
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- PSMC6 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- PSMC6 (Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 6 (PSMC6))
- Synonyms
- DDBDRAFT_0186051 Peptide, DDBDRAFT_0232968 Peptide, DDB_0186051 Peptide, DDB_0232968 Peptide, fb20g04 Peptide, wu:fb20g04 Peptide, wu:fc85c10 Peptide, cadp44 Peptide, sug2 Peptide, PSMC6 Peptide, psmc6-a Peptide, NV13405 Peptide, CADP44 Peptide, P44 Peptide, SUG2 Peptide, p42 Peptide, 2300001E01Rik Peptide, AI451058 Peptide, 26S protease regulatory subunit S10B Peptide, 26S proteasome regulatory subunit 10B Peptide, proteasome 26S subunit, ATPase 6 Peptide, proteasome 26S subunit, ATPase 6 L homeolog Peptide, 26S protease regulatory subunit 10B Peptide, proteasome 26S subunit, ATPase 6 S homeolog Peptide, proteasome (prosome, macropain) 26S subunit, ATPase, 6 Peptide, ATEG_02903 Peptide, HCAG_04181 Peptide, LOC5565051 Peptide, EDI_289460 Peptide, CpipJ_CPIJ003334 Peptide, EHI_194070 Peptide, PTRG_02716 Peptide, BDBG_01801 Peptide, psmC6 Peptide, MCYG_07206 Peptide, PITG_00229 Peptide, VDBG_04729 Peptide, MGYG_04704 Peptide, TERG_01608 Peptide, DICPUDRAFT_97252 Peptide, Tsp_02519 Peptide, prs10 Peptide, LOC100282100 Peptide, Psmc6 Peptide, psmc6 Peptide, psmc6.L Peptide, PSMC6 Peptide, LOC693577 Peptide, psmc6.S Peptide, LOC100117671 Peptide
- Background
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The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. Pseudogenes have been identified on chromosomes 8 and 12.
Alias Symbols: P44, p42, SUG2, CADP44, HEL-S-73
Protein Size: 389 - Gene ID
- 5706
- NCBI Accession
- NM_002806, NP_002797
- UniProt
- P62333
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