Interferon-Induced Transmembrane Protein 1 (IFITM1) (N-Term) Peptide
IFITM1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all IFITM1 products
- IFITM1 (Interferon-Induced Transmembrane Protein 1 (IFITM1))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- MHKEEHEVAV LGAPPSTILP RSTVINIHSE TSVPDHVVWS LFNTLFLNWC
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- IFITM1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- IFITM1 (Interferon-Induced Transmembrane Protein 1 (IFITM1))
- Synonyms
- 9-27 Peptide, CD225 Peptide, DSPA2a Peptide, IFI17 Peptide, LEU13 Peptide, 1110036C17Rik Peptide, Mil-2 Peptide, Mil2 Peptide, interferon induced transmembrane protein 1 Peptide, interferon induced transmembrane protein 1 (9-27) Peptide, Ifitm1 Peptide, IFITM1 Peptide
- Background
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IFN-induced antiviral protein which inhibits the entry of viruses to the host cell cytoplasm, permitting endocytosis, but preventing subsequent viral fusion and release of viral contents into the cytosol. Active against multiple viruses, including influenza A virus, SARS coronavirus (SARS-CoV), Marburg virus (MARV), Ebola virus (EBOV), Dengue virus (DNV), West Nile virus (WNV), human immunodeficiency virus type 1 (HIV-1) and hepatitis C virus (HCV). Can inhibit: influenza virus hemagglutinin protein-mediated viral entry, MARV and EBOV GP1,2-mediated viral entry and SARS-CoV S protein-mediated viral entry. Also implicated in cell adhesion and control of cell growth and migration. Plays a key role in the antiproliferative action of IFN-gamma either by inhibiting the ERK activation or by arresting cell growth in G1 phase in a p53-dependent manner. Acts as a positive regulator of osteoblast differentiation.
Alias Symbols: 9-27, CD225, IFI17, LEU13, DSPA2a
Protein Size: 125 - Gene ID
- 8519
- NCBI Accession
- NM_003641, NP_003632
- UniProt
- P13164
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