Polyhomeotic Homolog 3 (PHC3) (C-Term) Peptide
PHC3
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all PHC3 products
- PHC3 (Polyhomeotic Homolog 3 (PHC3))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- LSRWNRKPDN QSLGHRGRRP SGPDGAAREH ILRQLPITYP SAEEDLASHE
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-PHC3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- PHC3 (Polyhomeotic Homolog 3 (PHC3))
- Synonyms
- EDR3 Peptide, HPH3 Peptide, E030046K01Rik Peptide, Edr3 Peptide, Hph3 Peptide, polyhomeotic homolog 3 Peptide, polyhomeotic-like 3 (Drosophila) Peptide, Phc3 Peptide, PHC3 Peptide
- Background
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PHC3 is a component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.
Alias Symbols: PHC3,EDR3, PH3,
Protein Size: 983 - Gene ID
- 80012
- NCBI Accession
- XP_005247847
- UniProt
- Q8NDX5
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