Protein Phosphatase 2, Regulatory Subunit A, beta (PPP2R1B) (Middle Region) Peptide
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- Target See all PPP2R1B products
- PPP2R1B (Protein Phosphatase 2, Regulatory Subunit A, beta (PPP2R1B))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- CGLFSVCYPR ASNAVKAEIR QQFRSLCSDD TPMVRRAAAS KLGEFAKVLE
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- PPP2R1B Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- PPP2R1B (Protein Phosphatase 2, Regulatory Subunit A, beta (PPP2R1B))
- Synonyms
- 2410091N08Rik Peptide, AI790395 Peptide, PP2A-Abeta Peptide, PR65B Peptide, protein phosphatase 2, regulatory subunit A, beta Peptide, protein phosphatase 2 scaffold subunit Abeta Peptide, protein phosphatase 2 scaffold subunit A beta Peptide, protein phosphatase 2 regulatory subunit A, beta S homeolog Peptide, Ppp2r1b Peptide, PPP2R1B Peptide, ppp2r1b.S Peptide
- Background
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This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes a beta isoform of the constant regulatory subunit A. Mutations in this gene have been associated with some lung and colon cancers. Alternatively spliced transcript variants have been described.
Alias Symbols: PR65B, PP2A-Abeta
Protein Size: 556 - Gene ID
- 5519
- NCBI Accession
- NM_001177562, NP_001171033
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