Carboxypeptidase B2 (Plasma) (CPB2) (Middle Region) Peptide
CPB2
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all CPB2 products
- CPB2 (Carboxypeptidase B2 (Plasma) (CPB2))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- VASEAVRAIE KISKNTRYTH GHGSETLYLA PGGGDDWIYD LGIKYSFTIE
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- CPB2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- CPB2 (Carboxypeptidase B2 (Plasma) (CPB2))
- Synonyms
- CPU Peptide, PCPB Peptide, TAFI Peptide, 1110032P04Rik Peptide, 4930405E17Rik Peptide, AI255929 Peptide, CPR Peptide, Cpu Peptide, pCPB Peptide, zgc:112493 Peptide, carboxypeptidase B2 Peptide, carboxypeptidase B2 (plasma) Peptide, CPB2 Peptide, Cpb2 Peptide, cpb2 Peptide
- Background
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Carboxypeptidases are enzymes that hydrolyze C-terminal peptide bonds. The carboxypeptidase family includes metallo-, serine, and cysteine carboxypeptidases. According to their substrate specificity, these enzymes are referred to as carboxypeptidase A (cleaving aliphatic residues) or carboxypeptidase B (cleaving basic amino residues). The protein encoded by this gene is activated by trypsin and acts on carboxypeptidase B substrates. After thrombin activation, the mature protein downregulates fibrinolysis. Polymorphisms have been described for this gene and its promoter region. Alternate splicing results in multiple transcript variants.
Alias Symbols: CPU, PCPB, TAFI
Protein Size: 423 - Gene ID
- 1361
- NCBI Accession
- NM_001278541, NP_001265470
- UniProt
- Q96IY4
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