Interleukin 12 alpha (IL12A) (Middle Region) Peptide
IL12A
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all IL12A products
- IL12A (Interleukin 12 alpha (IL12A))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- SNMLQKARQT LEFYPCTSEE IDHEDITKDK TSTVEACLPL ELTKNESCLN
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-IL12A (ARP78125_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- IL12A (Interleukin 12 alpha (IL12A))
- Synonyms
- CLMF Peptide, IL-12A Peptide, NFSK Peptide, NKSF1 Peptide, P35 Peptide, CLMF2 Peptide, IL-12B Peptide, NKSF Peptide, NKSF2 Peptide, p40 Peptide, Il-12b Peptide, Il12p40 Peptide, Il-12p40 Peptide, Il12 Peptide, IL-12p40 Peptide, IL-12p35 Peptide, Il-12a Peptide, Ll12a Peptide, p35 Peptide, IL12p35 Peptide, Il-12 p35 Peptide, IL12p40 Peptide, IL12 Peptide, IL-12 p35 Peptide, interleukin 12A Peptide, interleukin 12B Peptide, interleukin 12b Peptide, interleukin 12a Peptide, Interleukin 12 level Peptide, IL12A Peptide, IL12B Peptide, Il12b Peptide, Il12a Peptide, IL12 Peptide, il12a Peptide
- Background
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This gene encodes a subunit of a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, and a 40-kD subunit that is a member of the cytokine receptor family. This cytokine is required for the T-cell-independent induction of interferon (IFN)-gamma, and is important for the differentiation of both Th1 and Th2 cells. The responses of lymphocytes to this cytokine are mediated by the activator of transcription protein STAT4. Nitric oxide synthase 2A (NOS2A/NOS2) is found to be required for the signaling process of this cytokine in innate immunity.
Alias Symbols: P35, CLMF, NFSK, NKSF1, IL-12A
Protein Size: 219 - Gene ID
- 3592
- NCBI Accession
- NM_000882, NP_000873
- UniProt
- P29459
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