UBX Domain Protein 1 (UBXN1) (N-Term) Peptide
UBXN1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all UBXN1 products
- UBXN1 (UBX Domain Protein 1 (UBXN1))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- GRAEKALALT GNQGIEAAMD WLMEHEDDPD VDEPLETPLG HILGREPTSS
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-UBXN1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- UBXN1 (UBX Domain Protein 1 (UBXN1))
- Synonyms
- 2B28 Peptide, SAKS1 Peptide, UBXD10 Peptide, 4930455J02Rik Peptide, D19Ertd721e Peptide, T25529 Peptide, RGD1309471 Peptide, fb49a05 Peptide, wu:fb49a05 Peptide, zgc:77531 Peptide, UBX domain protein 1 Peptide, UBXN1 Peptide, Ubxn1 Peptide, ubxn1 Peptide
- Background
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UBXN1 is a ubiquitin-binding protein that interacts with the BRCA1- BARD1 heterodimer, and regulates its activity. It specifically binds 'Lys-6'-linked polyubiquitin chains. Interaction with autoubiquitinated BRCA1,it leads to inhibit the E3 ubiquitin-protein ligase activity of the BRCA1-BARD1 heterodimer. It is a component of a complex required to couple deglycosylation and proteasome-mediated degradation of misfolded proteins in the endoplasmic reticulum that are retrotranslocated in the cytosol.
Alias Symbols: UBXN1,SAKS1,
Protein Size: 297 - Gene ID
- 51035
- UniProt
- Q04323
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