Protein Kinase Domain Containing, Cytoplasmic Homolog (Mouse) (PKDCC) (N-Term) Peptide
PKDCC
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all PKDCC products
- PKDCC (Protein Kinase Domain Containing, Cytoplasmic Homolog (Mouse) (PKDCC))
- Protein Region
- N-Term
- Origin
- Human
- Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- GGRGELARQI RARYEEVQRY SRGGPGPGAG RPERRRLMDL APGGPGLPRP
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-PKDCC Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- PKDCC (Protein Kinase Domain Containing, Cytoplasmic Homolog (Mouse) (PKDCC))
- Synonyms
- SGK493 Peptide, Vlk Peptide, AI115348 Peptide, AW548124 Peptide, Adtk1 Peptide, ESTM17 Peptide, MAd1 Peptide, Sgk493 Peptide, X83346 Peptide, RGD1311939 Peptide, protein kinase domain containing, cytoplasmic Peptide, PKDCC Peptide, Pkdcc Peptide
- Background
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Secreted tyrosine-protein kinase that mediates phosphorylation of extracellular proteins and endogenous proteins in the secretory pathway, which is essential for patterning at organogenesis stages. Mediates phosphorylation of MMP1, MMP13, MMP14, MMP19 and ERP29. Probably plays a role in platelets: rapidly and quantitatively secreted from platelets in response to stimulation of platelet degranulation. May also have serine/threonine protein kinase activity. Required for longitudinal bone growth through regulation of chondrocyte differentiation. May be indirectly involved in protein transport from the Golgi apparatus to the plasma membrane.
Alias Symbols: Vlk, SGK493
Protein Size: 493 - Gene ID
- 91461
- NCBI Accession
- NM_138370, NP_612379
- UniProt
- Q504Y2
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