Single-Minded Homolog 2 (SIM2) (Middle Region) Peptide
SIM2
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all SIM2 products
- SIM2 (Single-Minded Homolog 2 (SIM2))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- VLTEIEYKEL QLSLEQVSTA KSQDSWRTAL STSQETRKLV KPKNTKMKTK
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-SIM2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- SIM2 (Single-Minded Homolog 2 (SIM2))
- Synonyms
- Xsim2 Peptide, sim2-A Peptide, xSim Peptide, HMC13F06 Peptide, HMC29C01 Peptide, SIM Peptide, bHLHe15 Peptide, single-minded family bHLH transcription factor 2 S homeolog Peptide, single-minded family bHLH transcription factor 2 Peptide, single-minded homolog 2 (Drosophila) Peptide, sim2.S Peptide, sim2 Peptide, SIM2 Peptide, Sim2 Peptide
- Background
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This gene represents a homolog of the Drosophila single-minded (sim) gene, which encodes a transcription factor that is a master regulator of neurogenesis. The encoded protein is ubiquitinated by RING-IBR-RING-type E3 ubiquitin ligases, including the parkin RBR E3 ubiquitin protein ligase. This gene maps within the so-called Down syndrome chromosomal region, and is thus thought to contribute to some specific Down syndrome phenotypes. Alternative splicing of this gene results in multiple transcript variants.
Alias Symbols: SIM2,BHLHE15,
Protein Size: 667 - Gene ID
- 6493
- UniProt
- Q14190
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