Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8) (Middle Region) Peptide
SIGLEC8
Reactivity: Human
Host: Synthetic
WB
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- Target See all SIGLEC8 products
- SIGLEC8 (Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Western Blotting (WB)
- Sequence
- VRSCRKKSAR PAAGVGDTGM EDAKAIRGSA SQGPLTESWK DGNPLKKPPP
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Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8) peptide
SIGLEC8 Reactivity: Human Host: Synthetic BP, Imm
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- SIGLEC8 (Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8))
- Synonyms
- SAF2 Peptide, SIGLEC-8 Peptide, SIGLEC8L Peptide, SIGLEC8 Peptide, sialic acid binding Ig like lectin 8 Peptide, sialic acid-binding Ig-like lectin 8 Peptide, SIGLEC8 Peptide, LOC506364 Peptide
- Background
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Sialic acid-binding immunoglobulin (Ig)-like lectins, or SIGLECs (e.g., CD33 (MIM 159590)), are a family of type 1 transmembrane proteins each having a unique expression pattern, mostly in hemopoietic cells. SIGLEC8 is a member of the CD33-like subgroup of SIGLECs, which are localized to 19q13.3-q13.4 and have 2 conserved cytoplasmic tyrosine-based motifs: an immunoreceptor tyrosine-based inhibitory motif, or ITIM (see MIM 604964), and a motif homologous to one identified in signaling lymphocyte activation molecule (SLAM, MIM 603492) that mediates an association with SLAM-associated protein (SAP, MIM 300490) (summarized by Foussias et al., 2000 [PubMed 11095983]).[supplied by OMIM, May 2010]
Alias Symbols: SAF2, SIGLEC-8, SIGLEC8L
Protein Size: 201 - Gene ID
- 27181
- NCBI Accession
- NM_014442, NP_055257
- UniProt
- Q9NYZ4
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