CCR4-NOT Transcription Complex, Subunit 7 (CNOT7) (C-Term) Peptide
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- Target See all CNOT7 products
- CNOT7 (CCR4-NOT Transcription Complex, Subunit 7 (CNOT7))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Western Blotting (WB)
- Sequence
- MAFFKMREMF FEDHIDDAKY CGHLYGLGSG SSYVQNGTGN AYEEEANKQS
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- CNOT7 (CCR4-NOT Transcription Complex, Subunit 7 (CNOT7))
- Synonyms
- CNOT7 Peptide, CAF1 Peptide, fd59c07 Peptide, fj07d05 Peptide, wu:fd59c07 Peptide, wu:fj07d05 Peptide, zgc:153168 Peptide, caf1 Peptide, Caf1a Peptide, hCAF-1 Peptide, AU022737 Peptide, CAF-1 Peptide, Caf1 Peptide, Pop2 Peptide, CCR4-NOT transcription complex subunit 7 Peptide, ccr4-not transcription complex, subunit 7 Peptide, CCR4-NOT transcription complex, subunit 7 Peptide, ccr4-not transcription complex, subunit 7, putative Peptide, CCR4-NOT transcription complex subunit 7 S homeolog Peptide, CNOT7 Peptide, CNL04550 Peptide, GL50803_10606 Peptide, GL50803_8209 Peptide, CGB_D2510C Peptide, cnot7 Peptide, cnot7.S Peptide, Cnot7 Peptide
- Background
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The protein encoded by this gene binds to an anti-proliferative protein, B-cell translocation protein 1, which negatively regulates cell proliferation. Binding of the two proteins, which is driven by phosphorylation of the anti-proliferative protein, causes signaling events in cell division that lead to changes in cell proliferation associated with cell-cell contact. The encoded protein downregulates the innate immune response and therefore provides a therapeutic target for enhancing its antimicrobial activity against foreign agents. Alternate splicing of this gene results in two transcript variants encoding different isoforms.
Alias Symbols: CAF1, Caf1a, hCAF-1
Protein Size: 177 - Gene ID
- 29883
- NCBI Accession
- NM_013354, NP_037486
- UniProt
- Q9UIV1
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