Protein Kinase C, alpha (PKCa) (Middle Region) Peptide
PKCa
Reactivity: Human
Host: Synthetic
WB
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- Target See all PKC alpha (PKCa) products
- PKC alpha (PKCa) (Protein Kinase C, alpha (PKCa))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Western Blotting (WB)
- Sequence
- LRQKFEKAKL GPAGNKVISP SEDRKQPSNN LDRVKLTDFN FLMVLGKGSF
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- PKC alpha (PKCa) (Protein Kinase C, alpha (PKCa))
- Synonyms
- pkc-alpha Peptide, pkcalpha Peptide, im:7139045 Peptide, si:dkey-8l19.1 Peptide, LOC100219195 Peptide, AAG6 Peptide, PKC-alpha Peptide, PKCA Peptide, PRKACA Peptide, AI875142 Peptide, Pkca Peptide, PKRCA Peptide, protein kinase C alpha Peptide, protein kinase C, alpha L homeolog Peptide, protein kinase C, alpha Peptide, PRKCA Peptide, prkca.L Peptide, prkca Peptide, Prkca Peptide
- Background
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Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca(2+) handling in myocytes.
Alias Symbols: AAG6, PKCA, PRKACA, PKC-alpha
Protein Size: 672 - Gene ID
- 5578
- NCBI Accession
- NM_002737, NP_002728
- UniProt
- P17252
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