Mitogen-Activated Protein Kinase 8 (MAPK8) (N-Term) Peptide
MAPK8
Reactivity: Human
Host: Synthetic
WB
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- Target See all JNK (MAPK8) products
- JNK (MAPK8) (Mitogen-Activated Protein Kinase 8 (MAPK8))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Western Blotting (WB)
- Sequence
- MSRSKRDNNF YSVEIGDSTF TVLKRYQNLK PIGSGAQGIV CAAYDAILER
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- JNK (MAPK8) (Mitogen-Activated Protein Kinase 8 (MAPK8))
- Synonyms
- JNK Peptide, JNK-46 Peptide, JNK1 Peptide, JNK1A2 Peptide, JNK21B1/2 Peptide, PRKM8 Peptide, SAPK1 Peptide, SAPK1c Peptide, AI849689 Peptide, Prkm8 Peptide, BSK Peptide, BSK/DJNK Peptide, Bsk Peptide, CG5680 Peptide, D-JNK Peptide, D-junk Peptide, DBSK/JNK Peptide, DJNK Peptide, DJNK/bsk Peptide, Dmel\\CG5680 Peptide, JNK/SAPK Peptide, Jnk Peptide, Junk Peptide, SAPKa Peptide, c-Jun Peptide, dJNK Peptide, jnk Peptide, T10F20.15 Peptide, jnk1 Peptide, sapk1 Peptide, mapk8 Peptide, zgc:112379 Peptide, JNKb Peptide, mapk8b Peptide, mitogen-activated protein kinase 8 Peptide, Stress-activated protein kinase jnk-1 Peptide, basket Peptide, Protein kinase superfamily protein Peptide, mitogen-activated protein kinase 8 L homeolog Peptide, mitogen-activated protein kinase 8b Peptide, mitogen-activated protein kinase 8B-like Peptide, MAPK8 Peptide, jnk-1 Peptide, Mapk8 Peptide, bsk Peptide, ATMPK8 Peptide, mapk8.L Peptide, mapk8b Peptide, LOC109094263 Peptide
- Background
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The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Five alternatively spliced transcript variants encoding distinct isoforms have been reported.
Alias Symbols: JNK, JNK1, PRKM8, SAPK1, JNK-46, JNK1A2, SAPK1c, JNK21B1/2
Protein Size: 427 - Gene ID
- 5599
- NCBI Accession
- NM_001278547, NP_001265476
- UniProt
- P45983
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