N-Myc Proto-Oncogene Protein (MYCN) (Middle Region) Peptide
MYCN
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all MYCN products
- MYCN (N-Myc Proto-Oncogene Protein (MYCN))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- AAPAGAPGVA PPRPGGRQTS GGDHKALSTS GEDTLSDSDD EDDEEEDEEE
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- MYCN Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- MYCN (N-Myc Proto-Oncogene Protein (MYCN))
- Synonyms
- MODED Peptide, MYCNOT Peptide, N-myc Peptide, NMYC Peptide, ODED Peptide, bHLHe37 Peptide, Nmyc Peptide, Nmyc-1 Peptide, Nmyc1 Peptide, c-nmyc Peptide, Nmuc1 Peptide, fb57a02 Peptide, nmyc1 Peptide, wu:fb57a02 Peptide, zgc:85706 Peptide, XN-myc Peptide, XNmyc Peptide, mycn Peptide, mycn-a Peptide, mycn-b Peptide, mycna Peptide, xN-myc1 Peptide, MYCN proto-oncogene, bHLH transcription factor Peptide, v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog Peptide, v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived Peptide, olfactory receptor 8S1 Peptide, MYCN proto-oncogene, bHLH transcription factor S homeolog Peptide, MYCN Peptide, Mycn Peptide, LOC515887 Peptide, mycn Peptide, mycn.S Peptide
- Background
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This gene is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: NMYC, ODED, MODED, N-myc, bHLHe37
Protein Size: 464 - Gene ID
- 4613
- NCBI Accession
- NM_001293228, NP_001280157
- UniProt
- P04198
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