Dual Specificity Phosphatase 10 (DUSP10) (Middle Region) Peptide
DUSP10
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all DUSP10 products
- DUSP10 (Dual Specificity Phosphatase 10 (DUSP10))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- TTHLPLYHYE KGLFNYKRLP ATDSNKQNLR QYFEEAFEFI EEAHQCGKGL
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- DUSP10 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- DUSP10 (Dual Specificity Phosphatase 10 (DUSP10))
- Synonyms
- DUSP10 Peptide, MKP-5 Peptide, MKP5 Peptide, 2610306G15Rik Peptide, AI158871 Peptide, Mkp-5 Peptide, Mkp5 Peptide, dual specificity phosphatase 10 Peptide, DUSP10 Peptide, Dusp10 Peptide
- Background
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Dual specificity protein phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the MAP kinase superfamily, which is associated with cellular proliferation and differentiation. Different members of this family of dual specificity phosphatases show distinct substrate specificities for MAP kinases, different tissue distribution and subcellular localization, and different modes of expression induction by extracellular stimuli. This gene product binds to and inactivates p38 and SAPK/JNK. Alternative splicing results in multiple transcript variants.
Alias Symbols: MKP5, MKP-5
Protein Size: 482 - Gene ID
- 11221
- NCBI Accession
- NM_007207, NP_009138
- UniProt
- Q9Y6W6
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