Forkhead Box P2 (FOXP2) (N-Term) Peptide
FOXP2
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all FOXP2 products
- FOXP2 (Forkhead Box P2 (FOXP2))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- MQESATETIS NSSMNQNGMS TLSSQLDAGS RDGRSSGDTS SEVSTVELLH
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- FOXP2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- FOXP2 (Forkhead Box P2 (FOXP2))
- Synonyms
- CAGH44 Peptide, SPCH1 Peptide, TNRC10 Peptide, 2810043D05Rik Peptide, AI449000 Peptide, CAG-16 Peptide, D0Kist7 Peptide, RGD1559697 Peptide, FOXP2 Peptide, spch1 Peptide, cagh44 Peptide, tnrc10 Peptide, xlFoxP2 Peptide, foxP2 Peptide, foxP Peptide, Foxp2 Peptide, foxP2b Peptide, foxp2a Peptide, forkhead box P2 Peptide, lmw-gs Peptide, forkhead box transcription factor Peptide, forkhead box P2 L homeolog Peptide, FOXP2 Peptide, Foxp2 Peptide, foxp2 Peptide, foxP2 Peptide, foxp1c Peptide, foxp2.L Peptide
- Background
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This gene encodes a member of the forkhead/winged-helix (FOX) family of transcription factors. It is expressed in fetal and adult brain as well as in several other organs such as the lung and gut. The protein product contains a FOX DNA-binding domain and a large polyglutamine tract and is an evolutionarily conserved transcription factor, which may bind directly to approximately 300 to 400 gene promoters in the human genome to regulate the expression of a variety of genes. This gene is required for proper development of speech and language regions of the brain during embryogenesis, and may be involved in a variety of biological pathways and cascades that may ultimately influence language development. Mutations in this gene cause speech-language disorder 1 (SPCH1), also known as autosomal dominant speech and language disorder with orofacial dyspraxia. Multiple alternative transcripts encoding different isoforms have been identified in this gene.
Alias Symbols: SPCH1, CAGH44, TNRC10
Protein Size: 432 - Gene ID
- 93986
- NCBI Accession
- NM_001172766, NP_001166237
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