Phospholipase A2, Group III (PLA2G3) (C-Term) Peptide
PLA2G3
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all PLA2G3 products
- PLA2G3 (Phospholipase A2, Group III (PLA2G3))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- PPLDCVEGKN CSRDPRAIRV SARHLRRLQQ RRHQLQDKGT DERQPWPSEP
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- PLA2G3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- PLA2G3 (Phospholipase A2, Group III (PLA2G3))
- Synonyms
- PLA2G3 Peptide, GIII-SPLA2 Peptide, SPLA2III Peptide, 9130003P18Rik Peptide, phospholipase A2 group III Peptide, phospholipase A2, group III Peptide, PLA2G3 Peptide, Pla2g3 Peptide
- Background
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This gene encodes a protein that belongs to the secreted phospholipase A2 family, whose members include the bee venom enzyme. The encoded enzyme functions in lipid metabolism and catalyzes the calcium-dependent hydrolysis of the sn-2 acyl bond of phospholipids to release arachidonic acid and lysophospholipids. This enzyme acts as a negative regulator of ciliogenesis, and may play a role in cancer development by stimulating tumor cell growth and angiogenesis. This gene is associated with oxidative stress, and polymorphisms in this gene are linked to risk for Alzheimer's disease.
Alias Symbols: SPLA2III, sPLA2-III, GIII-SPLA2
Protein Size: 509 - Gene ID
- 50487
- NCBI Accession
- NM_015715, NP_056530
- UniProt
- Q9NZ20
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