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IgG3 (Middle Region) Peptide

Reactivity: Human Host: Synthetic WB, BP
Catalog No. ABIN5671649
  • Target See all IgG3 products
    IgG3
    Protein Region
    Middle Region
    Origin
    Human
    Source
    • 3
    Synthetic
    Application
    Western Blotting (WB), Blocking Peptide (BP)
    Sequence
    TKNQVSLTCL VKGFYPSDIA VEWESSGQPE NNYNTTPPML DSDGSFFLYS
    Characteristics
    This is a synthetic peptide designed for use in combination with anti- IGHG3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    IgG3
    Synonyms
    IgG3 Peptide, Immunoglobulin heavy constant gamma 3 Peptide, immunoglobulin heavy constant gamma 3 (G3m marker) Peptide, Ighg3 Peptide, IGHG3 Peptide
    Target Type
    Antibody
    Background
    Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens. The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen.

    Alias Symbols: IgG3

    Protein Size: 377
    Gene ID
    3502
    UniProt
    P01860
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