Ring Finger Protein 216 (RNF216) (Middle Region) Peptide
RNF216
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all RNF216 products
- RNF216 (Ring Finger Protein 216 (RNF216))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- TEDDEKLIEE IQKEAEEEQK RKNGENTFKR IGPPLEKPVE KVQRVEALPR
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- RNF216 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- RNF216 (Ring Finger Protein 216 (RNF216))
- Synonyms
- RGD1565135 Peptide, TRIAD3 Peptide, RNF216 Peptide, zin Peptide, u7i1 Peptide, triad3 Peptide, ubce7ip1 Peptide, MGC147026 Peptide, 2810055g22rik Peptide, 2810055G22Rik Peptide, AI647468 Peptide, AU019462 Peptide, C86502 Peptide, F830018F18Rik Peptide, UIP83 Peptide, Ubce7ip1 Peptide, CAHH Peptide, U7I1 Peptide, UBCE7IP1 Peptide, ZIN Peptide, ring finger protein 216 Peptide, Rnf216 Peptide, RNF216 Peptide, rnf216 Peptide
- Background
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This gene encodes a cytoplasmic protein which specifically colocalizes and interacts with the serine/threonine protein kinase, receptor-interacting protein (RIP). Zinc finger domains of the encoded protein are required for its interaction with RIP and for inhibition of TNF- and IL1-induced NF-kappa B activation pathways. The encoded protein may also function as an E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes and transfers it to substrates. Several alternatively spliced transcript variants have been described for this locus but the full-length natures of only some are known.
Alias Symbols: ZIN, CAHH, U7I1, TRIAD3, UBCE7IP1
Protein Size: 923 - Gene ID
- 54476
- NCBI Accession
- NM_207111, NP_996994
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