Fas Ligand (TNF Superfamily, Member 6) (FASL) (N-Term) Peptide
FASL
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all FASL products
- FASL (Fas Ligand (TNF Superfamily, Member 6) (FASL))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- APPGTVLPCP TSVPRRPGQR RPPPPPPPPP LPPPPPPPPL PPLPLPPLKK
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- FASLG Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- FASL (Fas Ligand (TNF Superfamily, Member 6) (FASL))
- Synonyms
- ALPS1B Peptide, APT1LG1 Peptide, APTL Peptide, CD178 Peptide, CD95-L Peptide, CD95L Peptide, FASL Peptide, TNFSF6 Peptide, fasl Peptide, Fas-L Peptide, Faslg Peptide, Tnfsf6 Peptide, gld Peptide, Apt1Lg1 Peptide, Fasl Peptide, FASLG Peptide, zgc:162027 Peptide, Fas ligand Peptide, Fas ligand L homeolog Peptide, Fas ligand (TNF superfamily, member 6) Peptide, FASLG Peptide, faslg.L Peptide, Fasl Peptide, Faslg Peptide, faslg Peptide
- Background
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This gene is a member of the tumor necrosis factor superfamily. The primary function of the encoded transmembrane protein is the induction of apoptosis triggered by binding to FAS. The FAS/FASLG signaling pathway is essential for immune system regulation, including activation-induced cell death (AICD) of T cells and cytotoxic T lymphocyte induced cell death. It has also been implicated in the progression of several cancers. Defects in this gene may be related to some cases of systemic lupus erythematosus (SLE). Alternatively spliced transcript variants have been described.
Alias Symbols: APTL, FASL, CD178, CD95L, ALPS1B, CD95-L, TNFSF6, TNLG1A, APT1LG1
Protein Size: 281 - Gene ID
- 356
- NCBI Accession
- NM_000639, NP_000630
- UniProt
- P48023
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