Fas Ligand (TNF Superfamily, Member 6) (FASL) Peptide
FASL
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all FASL products
- FASL (Fas Ligand (TNF Superfamily, Member 6) (FASL))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-FASLG antibody (Catalog #: AVARP02054_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- FASL (Fas Ligand (TNF Superfamily, Member 6) (FASL))
- Synonyms
- ALPS1B Peptide, APT1LG1 Peptide, APTL Peptide, CD178 Peptide, CD95-L Peptide, CD95L Peptide, FASL Peptide, TNFSF6 Peptide, fasl Peptide, Fas-L Peptide, Faslg Peptide, Tnfsf6 Peptide, gld Peptide, Apt1Lg1 Peptide, Fasl Peptide, FASLG Peptide, zgc:162027 Peptide, Fas ligand Peptide, Fas ligand L homeolog Peptide, Fas ligand (TNF superfamily, member 6) Peptide, FASLG Peptide, faslg.L Peptide, Fasl Peptide, Faslg Peptide, faslg Peptide
- Background
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TNFSF6 is a cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. May be involved in cytotoxic T cell mediated apoptosis and in T cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T cells, or both. Binding to the decoy receptor TNFRSF6B/DcR3 modulates its effects.
Alias Symbols: APT1LG1, CD178, CD95L, FASL, TNFSF6, CD95-L
Protein Interaction Partner: EGR2,EGR3,FNBP1,GRB2,PACSIN2,APBB1,DAXX,DMD,EZR,FADD,FAS,FN1,FNBP1,FYN,GRAP,GRAP2,GRB2,LCK,MLL,MMP7,NCF1,NCK1,PACSIN2,PDCD6,PIK3R1,PIN1,PRPF40A,PSTPIP1,PTPN13,SRC,SUMO1,TNFRSF6B,ARHGDIA,BID,CASP10,CASP8,EZR,FADD,FAS,FGR,FN1,FNBP1,FYN,GRAP,GRAP2,GRB2,LCK,LYN,MAPK8,MMP7,MSN,NCK1,PACSIN2,PTPN13,RHOA,SUMO1,TNFRSF10B,TNFRSF1A,TNFRSF6B,UBC
Protein Size: 281 - Molecular Weight
- 31 kDa
- Gene ID
- 356
- NCBI Accession
- NM_000639, NP_000630
- UniProt
- P48023
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