Nucleoporin 88kDa (NUP88) (Middle Region) Peptide
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- Target See all NUP88 products
- NUP88 (Nucleoporin 88kDa (NUP88))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- NYGYDACAVL CLPCVPNILV IATESGMLYH CVVLEGEEED DHTSEKSWDS
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- NUP88 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- NUP88 (Nucleoporin 88kDa (NUP88))
- Synonyms
- nup88B Peptide, nup88 Peptide, nup88A Peptide, Nup84 Peptide, Prei2 Peptide, nucleoporin 88 Peptide, nucleoporin 88kDa S homeolog Peptide, nucleoporin 88kDa L homeolog Peptide, nucleoporin 88kDa Peptide, NUP88 Peptide, nup88.S Peptide, nup88.L Peptide, nup88 Peptide, Nup88 Peptide
- Background
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The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins, a family of 50 to 100 proteins, are the main components of the nuclear pore complex in eukaryotic cells. The protein encoded by this gene belongs to the nucleoporin family and is associated with the oncogenic nucleoporin CAN/Nup214 in a dynamic subcomplex. This protein is also overexpressed in a large number of malignant neoplasms and precancerous dysplasias. Alternative splicing results in multiple transcript variants encoding different isoforms.
Protein Size: 741 - Gene ID
- 4927
- NCBI Accession
- NM_001320653, NP_001307582
- UniProt
- Q99567
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