Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A) (Middle Region) Peptide
GADD45A
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all GADD45A products
- GADD45A (Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- LLLLETDAGP AASEGAEQPP DLHCVLVTNP HSSQWKDPAL SQLICFCRES
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- GADD45A Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- GADD45A (Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A))
- Synonyms
- MGC53491 Peptide, zgc:91795 Peptide, gadd45a Peptide, GADD45A Peptide, ddit1 Peptide, gadd45 Peptide, GADD45 Peptide, AA545191 Peptide, Ddit1 Peptide, DDIT1 Peptide, Gadd45 Peptide, growth arrest and DNA damage inducible alpha L homeolog Peptide, growth arrest and DNA-damage-inducible, alpha, b Peptide, growth arrest and DNA damage inducible alpha Peptide, growth arrest and DNA damage-inducible protein 45 Peptide, growth arrest and DNA-damage-inducible 45 alpha Peptide, growth arrest and DNA-damage-inducible, alpha Peptide, gadd45a.L Peptide, gadd45ab Peptide, GADD45A Peptide, gadd45a Peptide, GADD45 Peptide, Gadd45a Peptide
- Background
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This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Alias Symbols: DDIT1, GADD45
Protein Size: 131 - Gene ID
- 1647
- NCBI Accession
- NM_001199741, NP_001186670
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