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TNFRSF1A-Associated Via Death Domain (TRADD) (N-Term) Peptide

TRADD Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN5672658
  • Target See all TRADD products
    TRADD (TNFRSF1A-Associated Via Death Domain (TRADD))
    Protein Region
    N-Term
    Origin
    Human
    Source
    • 2
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Sequence
    AAGQNGHEEW VGSAYLFVES SLDKVVLSDA YAHPQQKVAV YRALQAALAE
    Characteristics
    This is a synthetic peptide designed for use in combination with anti- TRADD Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    TRADD (TNFRSF1A-Associated Via Death Domain (TRADD))
    Synonyms
    TRADD Peptide, Hs.89862 Peptide, 9130005N23Rik Peptide, AA930854 Peptide, wu:fc59e02 Peptide, zgc:103556 Peptide, tradd Peptide, TNFRSF1A associated via death domain Peptide, conjugal transfer protein D Peptide, TNFRSF1A-associated via death domain Peptide, TNFRSF1A-associated via death domain L homeolog Peptide, tnfrsf1a-associated via death domain Peptide, TRADD Peptide, traDd Peptide, Tradd Peptide, tradd.L Peptide, tradd Peptide
    Background
    The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway.

    Alias Symbols: Hs.89862

    Protein Size: 312
    Gene ID
    8717
    NCBI Accession
    NM_001323552, NP_001310481
    UniProt
    Q15628
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