Mitochondrial Ribosomal Protein S22 (MRPS22) (Middle Region) Peptide
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- Target See all MRPS22 products
- MRPS22 (Mitochondrial Ribosomal Protein S22 (MRPS22))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- ILEGTETTKY VFTDISYSIP HRERFIVVRE PSGTLRKASW EERDRMIQVY
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- MRPS22 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- MRPS22 (Mitochondrial Ribosomal Protein S22 (MRPS22))
- Synonyms
- AAF56757 Peptide, CG12261 Peptide, Dmel\\CG12261 Peptide, MRP-S22 Peptide, MrpS22 Peptide, C3orf5 Peptide, COXPD5 Peptide, GIBT Peptide, RPMS22 Peptide, 3100002P07Rik Peptide, Rpms22 Peptide, DKFZp468F2212 Peptide, zgc:165596 Peptide, mitochondrial ribosomal protein S22 Peptide, 28S ribosomal protein S22, mitochondrial Peptide, mRpS22 Peptide, MRPS22 Peptide, Mrps22 Peptide, LOC726000 Peptide, mrps22 Peptide
- Background
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Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that does not seem to have a counterpart in prokaryotic and fungal-mitochondrial ribosomes. This gene lies telomeric of and is transcribed in the opposite direction from the forkhead box L2 gene. A pseudogene corresponding to this gene is found on chromosome Xq.
Alias Symbols: GIBT, GK002, C3orf5, COXPD5, RPMS22, MRP-S22
Protein Size: 360 - Gene ID
- 56945
- NCBI Accession
- NM_020191, NP_064576
- UniProt
- P82650
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