Eyes Absent Homolog 4 (EYA4) (Middle Region) Peptide
EYA4
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all EYA4 products
- EYA4 (Eyes Absent Homolog 4 (EYA4))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- IKDLDERTCR SSGSKSRGRG RKNNPSPPPD SDLERVFVWD LDETIIVFHS
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- EYA4 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- EYA4 (Eyes Absent Homolog 4 (EYA4))
- Synonyms
- B130023L16Rik Peptide, CMD1J Peptide, DFNA10 Peptide, EYA transcriptional coactivator and phosphatase 4 Peptide, Eya4 Peptide, EYA4 Peptide
- Background
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This gene encodes a member of the eyes absent (EYA) family of proteins. The encoded protein may act as a transcriptional activator through its protein phosphatase activity, and it may be important for eye development, and for continued function of the mature organ of Corti. Mutations in this gene are associated with postlingual, progressive, autosomal dominant hearing loss at the deafness, autosomal dominant non-syndromic sensorineural 10 locus. The encoded protein is also a putative oncogene that mediates DNA repair, apoptosis, and innate immunity following DNA damage, cellular damage, and viral attack. Defects in this gene are also associated with dilated cardiomyopathy 1J. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Alias Symbols: CMD1J, DFNA10
Protein Size: 639 - Gene ID
- 2070
- NCBI Accession
- NM_001301012, NP_001287941
- UniProt
- O95677
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