Nogo B Receptor (NUS1) (Middle Region) Peptide
NUS1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all Nogo B Receptor (NUS1) products
- Nogo B Receptor (NUS1)
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- YDHQGIFKRN NSRLMDEILK QQQELLGLDC SKYSPEFANS NDKDDQVLNC
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- NUS1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- Nogo B Receptor (NUS1)
- Synonyms
- C6orf68 Peptide, MGC:7199 Peptide, NgBR Peptide, TANGO14 Peptide, 1600027K07Rik Peptide, AU019165 Peptide, AW538011 Peptide, BC003223 Peptide, D10Ertd438e Peptide, NUS1 dehydrodolichyl diphosphate synthase subunit Peptide, NUS1 Peptide, Nus1 Peptide
- Background
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This gene encodes a type I single transmembrane domain receptor, which is a subunit of cis-prenyltransferase, and serves as a specific receptor for the neural and cardiovascular regulator Nogo-B. The encoded protein is essential for dolichol synthesis and protein glycosylation. This gene is highly expressed in non-small cell lung carcinomas as well as estrogen receptor-alpha positive breast cancer cells where it promotes epithelial mesenchymal transition. This gene is associated with the poor prognosis of human hepatocellular carcinoma patients. Naturally occurring mutations in this gene cause a congenital disorder of glycosylation and are associated with epilepsy. A knockout of the orthologous gene in mice causes embryonic lethality before day 6.5. Pseudogenes of this gene have been defined on chromosomes 13 and X.
Alias Symbols: NgBR, C6orf68, TANGO14, MGC:7199
Protein Size: 293 - Gene ID
- 116150
- NCBI Accession
- NM_138459, NP_612468
- UniProt
- Q96E22
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