Cleavage and Polyadenylation Factor I Subunit 1 (CLP1) (N-Term) Peptide
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- Target See all CLP1 products
- CLP1 (Cleavage and Polyadenylation Factor I Subunit 1 (CLP1))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- EANDDKKPTT KFELERETEL RFEVEASQSV QLELLTGMAE IFGTELTRNK
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- CLP1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- CLP1 (Cleavage and Polyadenylation Factor I Subunit 1 (CLP1))
- Synonyms
- Heab Peptide, RGD1307679 Peptide, AI462438 Peptide, ACDP1 Peptide, CLP-1 Peptide, CGP-39 Peptide, GP-39 Peptide, SPC-40 Peptide, SPS-40 Peptide, YKL-40 Peptide, HEAB Peptide, hClp1 Peptide, fa28a12 Peptide, wu:fa28a12 Peptide, clp1 Peptide, cleavage and polyadenylation factor I subunit 1 Peptide, CLP1, cleavage and polyadenylation factor I subunit Peptide, cyclin and CBS domain divalent metal cation transport mediator 1 Peptide, chitinase 3-like 1 (cartilage glycoprotein-39) Peptide, cleavage and polyadenylation factor I subunit 1 L homeolog Peptide, Clp1 Peptide, CNNM1 Peptide, CHI3L1 Peptide, CLP1 Peptide, clp1 Peptide, clp1.L Peptide
- Background
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This gene encodes a member of the Clp1 family. The encoded protein is a multifunctional kinase which is a component of the tRNA splicing endonuclease complex and a component of the pre-mRNA cleavage complex II. This protein is implicated in tRNA, mRNA, and siRNA maturation. Mutations in this gene are associated with pontocerebellar hypoplasia type 10 (PCH10). Alternatively splice transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: HEAB, hClp1
Protein Size: 425 - Gene ID
- 10978
- NCBI Accession
- NM_001142597, NP_001136069
- UniProt
- Q92989
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