Topoisomerase (DNA) III alpha (TOP3A) (C-Term) Peptide
TOP3A
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all TOP3A products
- TOP3A (Topoisomerase (DNA) III alpha (TOP3A))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- CLCSQPSVTR TVQKDGPNKG RQFHTCAKPR EQQCGFFQWV DENTAPGTSG
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- TOP3A Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- TOP3A (Topoisomerase (DNA) III alpha (TOP3A))
- Synonyms
- TOP3 Peptide, DNA topoisomerase III alpha Peptide, topoisomerase (DNA) III alpha Peptide, Top3a Peptide, TOP3A Peptide
- Background
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This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus reducing the number of supercoils and altering the topology of DNA. This enzyme forms a complex with BLM which functions in the regulation of recombination in somatic cells. Alternative splicing results in multiple transcript variants encoding different isoforms.
Alias Symbols: TOP3, ZGRF7
Protein Size: 906 - Gene ID
- 7156
- NCBI Accession
- NM_004618, NP_004609
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