beta-Site APP-Cleaving Enzyme 2 (BACE2) (Middle Region) Peptide
Quick Overview for beta-Site APP-Cleaving Enzyme 2 (BACE2) (Middle Region) Peptide (ABIN8095539)
Target
Origin
Source
Application
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Protein Region
- Middle Region
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Purpose
- BACE2 Peptide - middle region
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Sequence
- PAGAANFLAM VDNLQGDSGR GYYLEMLIGT PPQKLQILVD TGSSNFAVAG
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti- BACE2 Antibody (ARP84484_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- BACE2 (beta-Site APP-Cleaving Enzyme 2 (BACE2))
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Background
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Background Information: This gene encodes an integral membrane glycoprotein that functions as an aspartic protease. The encoded protein cleaves amyloid precursor protein into amyloid beta peptide, which is a critical step in the etiology of Alzheimer's disease and Down syndrome. The protein precursor is further processed into an active mature peptide. Alternative splicing results in multiple transcript variants.
Alternative Symbols: ASP1, BAE2, DRAP, AEPLC, ALP56, ASP21, CDA13, CEAP1
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Molecular Weight
- 51 kDa
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Gene ID
- 25825
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NCBI Accession
- NP_036237
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UniProt
- Q9Y5Z0
Target
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