Matrix Gla Protein (MGP) (AA 20-96) peptide (His tag)
MGP
Reactivity: Human
Host: Escherichia coli (E. coli)
SDS
1 image
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- Target See all MGP products
- MGP (Matrix Gla Protein (MGP))
- Peptide Type
- Recombinant
- Protein Region
- AA 20-96
- Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This MGP peptide is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MGSSHHHHHH SSGLVPRGSH MYESHESMES YELNPFINRR NANTFISPQQ RWRAKVQERI RERSKPVHEL NREACDDYRL CERYAMVYGYNAAYNRYF
- Characteristics
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Recombinant human MGP protein
Expression System: E.coli - Purity
- > 90 % pure
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- Application Notes
- MGP protein has been used in SDS PAGE, and may be suitable for use in other assays
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Liquid. 20 mM Tris-HCl buffer (pH8.0) containing 10 % glycerol.
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- 4 °C/-20 °C/-80 °C
- Storage Comment
- Can be stored at 4 °C short term (1-2 weeks). For long term storage, aliquot and store at -20 °C or -70 °C.
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- Target
- MGP (Matrix Gla Protein (MGP))
- Synonyms
- MGLAP Peptide, NTI Peptide, Mglap Peptide, mgp-A Peptide, MGP Peptide, LOC100136434 Peptide, mgp Peptide, matrix Gla protein Peptide, matrix Gla protein L homeolog Peptide, MGP Peptide, Mgp Peptide, mgp.L Peptide, mgp Peptide
- Background
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MGP, also known as Matrix Gla protein, is a protein involved in regulating calcification in the extracellular matrix, in particular in cartilage and arteries. MGP is a vitamin K-dependent protein, and contains five to six residues of Gla, a Ca2+ binding AA requiring vitamin K-dependent gamma carboxylase for its formation. It is found in human bone extracts, likely formed by COOH-terminal processing by carboxypeptidase B-like enzymatic activity. Recombinant human MGP protein, fused to His-tag at N-terminus, was expressed in E. coli and denatured using detergent during a conventional chromatography purification process.
Alternative Names: GIG36 protein, NTI protein, MGLAP protein, Matrix Gla protein isoform 2 precursor protein - Molecular Weight
- 11.8 kDa (98 AA)
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