TANK-Binding Kinase 1 (TBK1) Peptide
TBK1
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
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- Target See all TBK1 products
- TBK1 (TANK-Binding Kinase 1 (TBK1))
- Peptide Type
- Synthetic
- Origin
- Mammalian
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- EEETTTRHKV LIMEFCPCGS LYTVLEEPSN AYGLPESEFL IVLRDVVGGM
- Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of TBK1 antibody,
Alternative Names: TBK1 control peptide, TBK1 antibody Blocking Peptide, Anti-TBK1 Blocking Peptide, Tank-Binding Kinase 1 Blocking Peptide, FLJ11330 Blocking Peptide, NAK Blocking Peptide, T2K Blocking Peptide, TBK1, TBK-1, TBK 1, TBK-1 Blocking Peptide, TBK 1 Blocking Peptide
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- Application Notes
- Optimal conditions should be determined by the investigator
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
- Buffer
- PBS
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C long term.
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- Target
- TBK1 (TANK-Binding Kinase 1 (TBK1))
- Synonyms
- nak Peptide, t2k Peptide, TBK1 Peptide, wu:fk70c05 Peptide, zgc:136548 Peptide, NAK Peptide, T2K Peptide, 1200008B05Rik Peptide, AI462036 Peptide, AW048562 Peptide, TANK binding kinase 1 L homeolog Peptide, TANK binding kinase 1 Peptide, TANK-binding kinase 1 Peptide, tbk1.L Peptide, TBK1 Peptide, tbk1 Peptide, Tbk1 Peptide
- Background
- The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex. TBK1 is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors. For example, the protein can form a complex with the IKB protein TANK and TRAF2 and release the NFKB inhibition caused by TANK.
- Molecular Weight
- 84 kDa
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