KH Domain Containing, RNA Binding, Signal Transduction Associated 2 (KHDRBS2) Peptide
KHDRBS2
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
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- Target See all KHDRBS2 products
- KHDRBS2 (KH Domain Containing, RNA Binding, Signal Transduction Associated 2 (KHDRBS2))
- Peptide Type
- Synthetic
- Origin
- Mammalian
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- EEIEKFQGSD GKKEDEEKKY LDVISNKNIK LSERVLIPVK QYPKFNFVGK
- Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of KHDRBS2 antibody,
Alternative Names: KHDRBS2 control peptide, KHDRBS2 antibody Blocking Peptide, Anti-KHDRBS2 Blocking Peptide, KH domain containing, RNA binding, signal transduction associated 2 Blocking Peptide, FLJ38664 Blocking Peptide, MGC26664 Blocking Peptide, SLM-1 Blocking Peptide, SLM1 Blocking Peptide, bA535F17.1 Blocking Peptide, KHDRBS2, KHDRBS-2, KHDRBS 2, KHDRBS-2 Blocking Peptide, KHDRBS 2 Blocking Peptide
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- Application Notes
- Optimal conditions should be determined by the investigator
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
- Buffer
- PBS
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C long term.
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- Target
- KHDRBS2 (KH Domain Containing, RNA Binding, Signal Transduction Associated 2 (KHDRBS2))
- Synonyms
- slm1 Peptide, slm-1 Peptide, MGC145973 Peptide, ba535f17.1 Peptide, zgc:153588 Peptide, SLM-1 Peptide, SLM1 Peptide, bA535F17.1 Peptide, 6330586C16Rik Peptide, Slim1 Peptide, Slm1 Peptide, KH RNA binding domain containing, signal transduction associated 2 Peptide, KH domain containing, RNA binding, signal transduction associated 2 Peptide, KHDRBS2 Peptide, khdrbs2 Peptide, Khdrbs2 Peptide
- Background
- KHDRBS2 is a RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. Its phosphorylation by FYN inhibits its ability to regulate splice site selection. KHDRBS2 induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer. KHDRBS2 may function as an adapter protein for Src kinases during mitosis. KHDRBS2 binds both poly(A) and poly(U) homopolymers. Phosphorylation by PTK6 inhibits its RNA-binding ability.
- Molecular Weight
- 39 kDa
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