KH Domain Containing, RNA Binding, Signal Transduction Associated 2 (KHDRBS2) (N-Term) Peptide
KHDRBS2
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all KHDRBS2 products
- KHDRBS2 (KH Domain Containing, RNA Binding, Signal Transduction Associated 2 (KHDRBS2))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- EEIEKFQGSD GKKEDEEKKY LDVISNKNIK LSERVLIPVK QYPKFNFVGK
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-KHDRBS2 Antibody(ARP53109_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- KHDRBS2 (KH Domain Containing, RNA Binding, Signal Transduction Associated 2 (KHDRBS2))
- Synonyms
- slm1 Peptide, slm-1 Peptide, MGC145973 Peptide, ba535f17.1 Peptide, zgc:153588 Peptide, SLM-1 Peptide, SLM1 Peptide, bA535F17.1 Peptide, 6330586C16Rik Peptide, Slim1 Peptide, Slm1 Peptide, KH RNA binding domain containing, signal transduction associated 2 Peptide, KH domain containing, RNA binding, signal transduction associated 2 Peptide, KHDRBS2 Peptide, khdrbs2 Peptide, Khdrbs2 Peptide
- Background
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KHDRBS2 is a RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. Its phosphorylation by FYN inhibits its ability to regulate splice site selection. KHDRBS2 induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer. KHDRBS2 may function as an adapter protein for Src kinases during mitosis. KHDRBS2 binds both poly(A) and poly(U) homopolymers. Phosphorylation by PTK6 inhibits its RNA-binding ability.
Alias Symbols: FLJ38664, MGC26664, SLM-1, SLM1, bA535F17.1
Protein Interaction Partner: EWSR1,GRB2,HNRNPK,KHDRBS3,PRMT1,RBMX,YTHDC1,ARID2,DDX17,DDX5,DEK,DSG1,EHBP1,EWSR1,FBXW11,FGA,FGB,FGG,HNRNPA0,HNRNPA1,HNRNPA2B1,HNRNPC,HNRNPD,HNRNPH1,HNRNPH3,HNRNPK,HNRNPL,HNRNPR,HNRNPUL2,HNRPDL,HRNR,HSP90AB1,IGF2BP1,IGF2BP3,ILF2,ILF3,KHDRBS1,KHDRBS3,LRRC1
Protein Size: 349 - Molecular Weight
- 39 kDa
- Gene ID
- 202559
- NCBI Accession
- NM_152688, NP_689901
- UniProt
- Q5VWX1
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