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Angiotensinogen (serpin Peptidase Inhibitor, Clade A, Member 8) (AGT) Peptide

AGT Reactivity: Mammalian Host: Synthetic WB, BP, IHC
Catalog No. ABIN939371
  • Target See all AGT products
    AGT (Angiotensinogen (serpin Peptidase Inhibitor, Clade A, Member 8) (AGT))
    Peptide Type
    Synthetic
    Origin
    Mammalian
    Source
    • 4
    Synthetic
    Application
    Western Blotting (WB), Blocking Peptide (BP), Immunohistochemistry (IHC)
    Sequence
    IHPFHLVIHN ESTCEQLAKA NAGKPKDPTF IPAPIQAKTS PVDEKALQDQ
    Characteristics
    A synthetic peptide for use as a blocking control in assays to test for specificity of AGT antibody,
    Alternative Names: AGT control peptide, AGT antibody Blocking Peptide, Anti-AGT Blocking Peptide, Angiotensinogen Blocking Peptide, Serpin Peptidase Inhibitor Clade A 8 Blocking Peptide, ANHU Blocking Peptide, SERPINA8 Blocking Peptide
  • Application Notes
    Optimal conditions should be determined by the investigator
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
    Buffer
    PBS
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C long term.
  • Target
    AGT (Angiotensinogen (serpin Peptidase Inhibitor, Clade A, Member 8) (AGT))
    Synonyms
    ANHU Peptide, SERPINA8 Peptide, AI265500 Peptide, AngI Peptide, AngII Peptide, Aogen Peptide, Serpina8 Peptide, ANRT Peptide, Ang Peptide, PAT Peptide, wu:fb62f06 Peptide, wu:fj87b02 Peptide, zgc:111892 Peptide, AGT Peptide, angt Peptide, ANGT Peptide, angiotensinogen Peptide, angiotensinogen (serpin peptidase inhibitor, clade A, member 8) Peptide, AGT Peptide, Agt Peptide, agt Peptide
    Background
    AGT, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease.
    Molecular Weight
    53 kDa
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