AP2 associated kinase 1 (AAK1) (C-Term) Peptide
AAK1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all AAK1 products
- AAK1 (AP2 associated kinase 1 (AAK1))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- SGFDVPEGSD KVAEDEFDPI PVLITKNPQG GHSRNSSGSS ESSLPNLARS
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-AAK1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- AAK1 (AP2 associated kinase 1 (AAK1))
- Synonyms
- 5530400K14Rik Peptide, 9630042K20 Peptide, AU067724 Peptide, AU067726 Peptide, BC028270 Peptide, C79663 Peptide, D6Ertd245e Peptide, R75501 Peptide, mKIAA1048 Peptide, RGD1563580 Peptide, aak1 Peptide, si:dkey-261l11.5 Peptide, AP2 associated kinase 1 Peptide, uncharacterized protein FLJ45252 Peptide, AP2 associated kinase 1b Peptide, AAK1 Peptide, Aak1 Peptide, LOC100512341 Peptide, aak1b Peptide
- Background
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Adaptor-related protein complex 2 (AP-2 complexes) functions during receptor-mediated endocytosis to trigger clathrin assembly, interact with membrane-bound receptors, and recruit encodytic accessory factors. This gene encodes a member of the SNF1 subfamily of Ser/Thr protein kinases. The protein interacts with and phosphorylates a subunit of the AP-2 complex, which promotes binding of AP-2 to sorting signals found in membrane-bound receptors and subsequent receptor endocytosis. Its kinase activity is stimulated by clathrin. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
Alias Symbols: DKFZp686F03202, DKFZp686K16132, FLJ23712, FLJ25931, FLJ31060, FLJ42882, FLJ45252, KIAA1048, MGC138170, MGC164568, MGC164570
Protein Size: 961 - Molecular Weight
- 104 kDa
- Gene ID
- 22848
- NCBI Accession
- NM_014911, NP_055726
- UniProt
- Q2M2I8
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