ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 1 (ABCC1) (Middle Region) Peptide
ABCC1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all ABCC1 products
- ABCC1 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 1 (ABCC1))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-ABCC1 antibody (Catalog #: ARP43653_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 1 (ABCC1) peptide
ABCC1 Reactivity: Human, Cow, Mouse, Rat, Dog Host: Synthetic BP, Imm
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- ABCC1 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 1 (ABCC1))
- Synonyms
- ABC29 Peptide, ABCC Peptide, GS-X Peptide, MRP Peptide, MRP1 Peptide, Abcc1a Peptide, Abcc1b Peptide, Mdrap Peptide, Mrp1 Peptide, Avcc1a Peptide, Mrp Peptide, ABCC13 Peptide, ATP binding cassette subfamily C member 1 Peptide, ATP-binding cassette, sub-family C (CFTR/MRP), member 1 Peptide, multidrug resistance-associated protein 1 Peptide, ABCC1 Peptide, Abcc1 Peptide, LOC100152428 Peptide, LOC100346553 Peptide
- Background
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ABCC1 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts. Alternative splicing by exon deletion results in several splice variants but maintains the original open reading frame in all forms. The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts. Alternative splicing by exon deletion results in several splice variants but maintains the original open reading frame in all forms.
Alias Symbols: ABC29, ABCC, DKFZp686N04233, DKFZp781G125, GS-X, MRP, MRP1
Protein Size: 1531 - Molecular Weight
- 171 kDa
- Gene ID
- 4363
- NCBI Accession
- NM_004996, NP_004987
- UniProt
- P33527
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