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ATP-Binding Cassette, Sub-Family D (Ald), Member 4 (ABCD4) (N-Term) Peptide

ABCD4 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN972740
  • Target See all ABCD4 products
    ABCD4 (ATP-Binding Cassette, Sub-Family D (Ald), Member 4 (ABCD4))
    Protein Region
    N-Term
    Origin
    Human
    Source
    • 6
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-ABCD4 antibody (Catalog #: ARP43655_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    ABCD4 (ATP-Binding Cassette, Sub-Family D (Ald), Member 4 (ABCD4))
    Synonyms
    ABC41 Peptide, EST352188 Peptide, MAHCJ Peptide, P70R Peptide, P79R Peptide, PMP69 Peptide, PXMP1L Peptide, Pxmp1l Peptide, ABCD4 Peptide, zgc:153503 Peptide, P69r Peptide, ATP binding cassette subfamily D member 4 Peptide, ATP-binding cassette, sub-family D (ALD), member 4 Peptide, ABCD4 Peptide, Abcd4 Peptide, abcd4 Peptide
    Background
    ABCD4 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown. However, it is speculated that it may function as a heterodimer for another peroxisomal ABC transporter and, therefore, may modify the adrenoleukodystrophy phenotype. It may also play a role in the process of peroxisome biogenesis. The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown. However, it is speculated that it may function as a heterodimer for another peroxisomal ABC transporter and, therefore, may modify the adrenoleukodystrophy phenotype. It may also play a role in the process of peroxisome biogenesis. Alternative splicing results in at least two different transcript variants, one which is protein-coding and one which is probably not protein-coding.

    Alias Symbols: ABC41, EST352188, P70R, P79R, PMP69, PXMP1L

    Protein Interaction Partner: PEA15,TMEM66,XRCC6,DLEU1,PEA15,XRCC6

    Protein Size: 606
    Molecular Weight
    68 kDa
    Gene ID
    5826
    NCBI Accession
    NM_005050, NP_005041
    UniProt
    O14678
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