Amiloride-Sensitive Cation Channel 4, Pituitary (ACCN4) (Middle Region) Peptide
ACCN4
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all ACCN4 products
- ACCN4 (Amiloride-Sensitive Cation Channel 4, Pituitary (ACCN4))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- NLTRYGKEIS MVRIPNRGSA RYLARKYNRN ETYIRENFLV LDVFFEALTS
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-ACCN4 Antibody(ARP35288_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- ACCN4 (Amiloride-Sensitive Cation Channel 4, Pituitary (ACCN4))
- Synonyms
- ACCN4 Peptide, BNAC4 Peptide, Accn4 Peptide, Spasic Peptide, acid sensing ion channel subunit family member 4 S homeolog Peptide, acid sensing ion channel subunit family member 4 Peptide, acid-sensing (proton-gated) ion channel family member 4 Peptide, asic4.S Peptide, ASIC4 Peptide, Asic4 Peptide
- Background
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ACCN4 belongs to the superfamily of acid-sensing ion channels, which are proton-gated, amiloride-sensitive sodium channels. These channels have been implicated in synaptic transmission, pain perception as well as mechanoperception. ACCN4 is predominantly expressed in the pituitary gland, and might be a candidate for paroxysmal dystonic choreoathetosis (PDC), a movement disorder.
Alias Symbols: ASIC4, BNAC4, MGC17248, MGC24860, ACCN4
Protein Size: 666 - Molecular Weight
- 73 kDa
- Gene ID
- 55515
- NCBI Accession
- NM_018674, NP_061144
- UniProt
- Q96FT7
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