Angiotensin II Receptor, Type 2 (AGTR2) (N-Term) Peptide
AGTR2
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all Angiotensin II Type 2 Receptor (AGTR2) products
- Angiotensin II Type 2 Receptor (AGTR2) (Angiotensin II Receptor, Type 2 (AGTR2))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- LHFGLVNISG NNESTLNCSQ KPSDKHLDAI PILYYIIFVI GFLVNIVVVT
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-AGTR2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- Angiotensin II Type 2 Receptor (AGTR2) (Angiotensin II Receptor, Type 2 (AGTR2))
- Synonyms
- AT2 Peptide, ATGR2 Peptide, MRX88 Peptide, AI316812 Peptide, AW107640 Peptide, AT2-R Peptide, AT2R Peptide, AT2R Peptide, at2 Peptide, zgc:113016 Peptide, AGTR2 Peptide, angiotensin II receptor type 2 Peptide, angiotensin II receptor, type 2 Peptide, AGTR2 Peptide, Agtr2 Peptide, agtr2 Peptide
- Background
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The protein encoded by this gene belongs to the G-protein coupled receptor 1 family, and functions as a receptor for angiotensin II. It is an intergral membrane protein that is highly expressed in fetus, but scantily in adult tissues, except brain, adrenal medulla, and atretic ovary. This receptor has been shown to mediate programmed cell death and this apoptotic function may play an important role in developmental biology and pathophysiology. Mutations in this gene are been associated with X-linked mental retardation.
Alias Symbols: AT2, ATGR2, MRX88
Protein Interaction Partner: ACE,AGT,ERBB3,GNAI2,GNAI3,MTUS1,PIK3CB,ZBTB16,AGTRAP,MTUS1
Protein Size: 363 - Molecular Weight
- 41 kDa
- Gene ID
- 186
- NCBI Accession
- NM_000686, NP_000677
- UniProt
- P50052
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