Aldehyde Dehydrogenase 1 Family, Member A2 (ALDH1A2) (N-Term) Peptide
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- Target See all ALDH1A2 products
- ALDH1A2 (Aldehyde Dehydrogenase 1 Family, Member A2 (ALDH1A2))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- PVYNPATGEQ VCEVQEADKA DIDKAVQAAR LAFSLGSVWR RMDASERGRL
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-ALDH1A2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- ALDH1A2 (Aldehyde Dehydrogenase 1 Family, Member A2 (ALDH1A2))
- Synonyms
- Raldh-2 Peptide, RALDH(II) Peptide, RALDH2 Peptide, RALDH2-T Peptide, fb50h01 Peptide, raldh2 Peptide, AV116159 Peptide, Aldh1a7 Peptide, Raldh1 Peptide, Raldh2 Peptide, aldehyde dehydrogenase 1 family, member A2 Peptide, aldehyde dehydrogenase 1 family member A2 Peptide, aldehyde dehydrogenase family 1, subfamily A2 Peptide, Aldh1a2 Peptide, ALDH1A2 Peptide, aldh1a2 Peptide
- Background
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This protein belongs to the aldehyde dehydrogenase family of proteins. The product of this gene is an enzyme that catalyzes the synthesis of retinoic acid (RA) from retinaldehyde. Retinoic acid, the active derivative of vitamin A (retinol), is a hormonal signaling molecule that functions in developing and adult tissues. The studies of a similar mouse gene suggest that this enzyme and the cytochrome CYP26A1, concurrently establish local embryonic retinoic acid levels which facilitate posterior organ development and prevent spina bifida. Three transcript variants encoding distinct isoforms have been identified for this gene.
Alias Symbols: MGC26444, RALDH(II), RALDH2, RALDH2-T
Protein Size: 518 - Molecular Weight
- 57 kDa
- Gene ID
- 8854
- NCBI Accession
- NM_003888, NP_003879
- UniProt
- O94788
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