Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 1 (APBA1) Peptide
APBA1
Reactivity: Human
Host: Synthetic
BP, IHC, WB
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- Target See all APBA1 products
- APBA1 (Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 1 (APBA1))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-APBA1 antibody (Catalog #: AVARP13059_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- APBA1 (Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 1 (APBA1))
- Synonyms
- APBA1 Peptide, 6430513E09Rik Peptide, Lin-10 Peptide, Mint Peptide, Mint1 Peptide, Urop11 Peptide, X11 Peptide, X11alpha Peptide, D9S411E Peptide, LIN10 Peptide, MINT1 Peptide, X11A Peptide, X11ALPHA Peptide, amyloid beta precursor protein binding family A member 1 Peptide, amyloid beta (A4) precursor protein-binding, family A, member 1b Peptide, ketopantoate reductase Peptide, 2-dehydropantoate 2-reductase Peptide, amyloid beta (A4) precursor protein-binding, family A, member 1 (X11) Peptide, amyloid beta (A4) precursor protein-binding, family A, member 1 Peptide, amyloid beta (A4) precursor protein binding, family A, member 1 Peptide, APBA1 Peptide, apba1b Peptide, apbA1 Peptide, apba1 Peptide, Apba1 Peptide
- Background
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APBA1 is a member of the X11 protein family. It is a neuronal adaptor protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilises APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. APBA1 is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion.
Alias Symbols: D9S411E, MINT1, X11, X11A, X11ALPHA, LIN10
Protein Interaction Partner: APP,APP,NOTCH1,APBB1,CASK,CCS,APP,CACNA1B,CASK,CCS,CNTNAP3,CNTNAP4,HTR2C,KCNJ12,KIF17,LIN7B,NOTCH1,NRXN1,PSEN1,STX1A,STXBP1,APP,CASK,CCS,CNTNAP3,CNTNAP4,DLG1,HTR2C,KCNJ12,LIN7A,LIN7B,LIN7C,PSEN2
Protein Size: 474 - Molecular Weight
- 52 kDa
- Gene ID
- 320
- NCBI Accession
- NM_001163
- UniProt
- Q02410
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